Synthesis and antimicrobial activity of some pyridinium salts.

نویسندگان

  • Vildan Alptüzün
  • Sülünay Parlar
  • Hüseyin Taşli
  • Ercin Erciyas
چکیده

Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains.

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عنوان ژورنال:
  • Molecules

دوره 14 12  شماره 

صفحات  -

تاریخ انتشار 2009